PaO₂/FiO₂ Ratio
Horovitz Index for Lung function
PaO₂
FiO₂
FiO₂: fraction of inspired oxygen; PaO₂: partial pressure of oxygen in arterial blood
PaO₂/FiO₂ Ratio
Answer all questions to see the result
Informații suplimentare
Avertizare
Acest instrument este destinat exclusiv scopurilor educaționale și nu constituie consultație de specialitate sau substitut pentru consultațiile de specialitate. Instrumentul nu trebuie folosit pentru diagnosticarea medicală și/sau acordarea tratamentului medical corespunzător.
General description
Acute respiratory distress syndrome (ARDS) is a form of inflammatory lung injury associated with high mortality. ARDS and its severity grading are defined mainly by the P/F ratio, also known as the Horovitz index, which is calculated by dividing the arterial partial pressure of oxygen (PaO₂) with the inspired oxygen concentration (FiO₂) and represents a measure of hypoxemia.
The 2012 Berlin definition of ARDS recognizes 3 grades of ARDS severity: mild (P/F ratio 201–300 mmHg), moderate (P/F ratio 101–200 mmHg), and severe (P/F ratio ≤ 100 mmHg), each associated with considerably increased mortality (27 %, 32 %, and 45 % respectively). As P/F ratio can be markedly affected by the positive end-expiratory pressure (PEEP), a minimum level of PEEP (≥ 5 cm H₂O) was also included in the definition of ARDS.
Acute respiratory distress syndrome (ARDS) is a form of inflammatory lung injury associated with high mortality. ARDS and its severity grading are defined mainly by the P/F ratio, also known as the Horovitz index, which is calculated by dividing the arterial partial pressure of oxygen (PaO₂) with the inspired oxygen concentration (FiO₂) and represents a measure of hypoxemia.
The 2012 Berlin definition of ARDS recognizes 3 grades of ARDS severity: mild (P/F ratio 201–300 mmHg), moderate (P/F ratio 101–200 mmHg), and severe (P/F ratio ≤ 100 mmHg), each associated with considerably increased mortality (27 %, 32 %, and 45 % respectively). As P/F ratio can be markedly affected by the positive end-expiratory pressure (PEEP), a minimum level of PEEP (≥ 5 cm H₂O) was also included in the definition of ARDS.
Formula
Horowitz Index is calculated as PaO₂ [mmHg] divided by FiO₂.
ARDS severity
Not ARDS
> 300 mmHgMild ARDS
201–300 mmHgModerate ARDS
101–200 mmHgSevere ARDS
< 101 mmHgReferences
ARDS Definition Task Force et al. “Acute respiratory distress syndrome: the Berlin Definition.” JAMA vol. 307,23 (2012): 2526-33. doi:10.1001/jama.2012.5669
Griffiths, Mark J D et al. “Guidelines on the management of acute respiratory distress syndrome.” BMJ open respiratory research vol. 6,1 e000420. 24 May. 2019, doi:10.1136/bmjresp-2019-000420
Tasaka, Sadatomo et al. “ARDS Clinical Practice Guideline 2021.” Journal of intensive care vol. 10,1 32. 8 Jul. 2022, doi:10.1186/s40560-022-00615-6
Horovitz, J H et al. “Pulmonary response to major injury.” Archives of surgery (Chicago, Ill. : 1960) vol. 108,3 (1974): 349-55. doi:10.1001/archsurg.1974.01350270079014
Versiune
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Despre acest instrument
Acute respiratory distress syndrome (ARDS) is a form of inflammatory lung injury associated with high mortality. ARDS and its severity grading are defined mainly by the P/F ratio, also known as the Horovitz index, which is calculated by dividing the arterial partial pressure of oxygen (PaO₂) with the inspired oxygen concentration (FiO₂) and represents a measure of hypoxemia.
The 2012 Berlin definition of ARDS recognizes 3 grades of ARDS severity: mild (P/F ratio 201–300 mmHg), moderate (P/F ratio 101–200 mmHg), and severe (P/F ratio ≤ 100 mmHg), each associated with considerably increased mortality (27 %, 32 %, and 45 % respectively). As P/F ratio can be markedly affected by the positive end-expiratory pressure (PEEP), a minimum level of PEEP (≥ 5 cm H₂O) was also included in the definition of ARDS.
The 2012 Berlin definition of ARDS recognizes 3 grades of ARDS severity: mild (P/F ratio 201–300 mmHg), moderate (P/F ratio 101–200 mmHg), and severe (P/F ratio ≤ 100 mmHg), each associated with considerably increased mortality (27 %, 32 %, and 45 % respectively). As P/F ratio can be markedly affected by the positive end-expiratory pressure (PEEP), a minimum level of PEEP (≥ 5 cm H₂O) was also included in the definition of ARDS.
