Sequential Organ Failure Assessment Score (SOFA)

Ova alatka služi isključivo u obrazovne svrhe i ne predstavlja profesionalni savet niti zamenu za profesionalni savet. Alatku ne treba koristiti za postavljanje medicinske dijagnoze i/ili pružanje medicinske terapije.

Opšti opis
Skor sekvencijalne procene insuficijencije organa (SOFA) koristi se za praćenje stanja pacijenta tokom boravka u odeljenju intenzivne nege i za određivanje stepena pacijentove funkcije organa ili stope insuficijencije. Ovaj skor se zasniva na šest različitih vrednosti, po jedne za respiratorni, kardiovaskularni, jetreni, koagulacioni, bubrežni i neurološki sistem.

Respiration
PaO₂/FiO₂ × 100, mmHg

• < 400 - (1 point)
• < 300 - (2 points)
• < 200* - (3 points)
• < 100* - (4 points)

*With respiratory support

Coagulation
Platelets ×10³/mm³

• < 150 - (1 point)
• < 100 - (2 points)
• < 50 - (3 points)
• < 20 - (4 points)

Liver
Bilirubun, mg/dl (µmol/l)

• 1,2-1,9 (20-32) - (1 point)
• 2-5,9 (33-101) - (2 points)
• 6-11,9 (102-204) - (3 points)
• > 12 (> 204) - (4 points)

Cardiovascular
Hypotension

• MAP < 70 mmHg - (1 point)
• Dopamine ≤ 5 or dobutamine (any dose)¹ - (2 points)
• Dopamine > 5 or epinephrine ≤ 0,1 or norepinephrine ≤ 0,1 - (3 points)
• Dopamine > 15 or epinephrine > 0,1or norepinephrine > 0,1 - (4 points)

¹Adrenergic agents administered for at least 1h (doses given are in µg/kg/min)

Central nervous system
Glasgow Coma Score

• 13-14 - (1 point)
• 10-12 - (2 points)
• 6-9 - (3 points)
• < 6 - (4 points)

Renal
Creatinine, mg/dl (µmol/l) or urine output

• 1.2-1.9 (110-170) - (1 point)
• 2.0-3.4 (171-299) - (2 points)
• 3.5-4.9 (300-440) or < 500 ml/day - (3 points)
• > 5.0 (> 440) or < 200 ml/day - (4 points)

Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996;22:707–710.

Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315(8):801-810.